99无码不卡中文字幕在线视频_理论国产无码在线_久久综合国产乱子伦精免费_国产传媒日韩欧美成人动漫精品免费观看

產(chǎn)品中心

PCAF (Acetyl Lys428) rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES1127
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: PCAF (Acetyl Lys428) rabbit pAb
Reactivity: Human;Mouse
Alternative Names: KAT2B; PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized acetyl-peptide derived from the human PCAF around the acetylation site of K428.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 93kD
GeneID: 8850
Human Swiss-Prot No: Q92831
Cellular localization: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . Mainly localizes to the nucleus. Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation. Subcellular location may vary depending upon cell differentiation state. Cytoplasmic at the very stages of keratinocyte differentiation, becomes nuclear at later differentiation stages. Cytoplasmic in basal epithelial cells (undifferentiated cells) and nuclear in parabasal cells (differentiated cells) (PubMed:20940255). .
Background: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008],
關(guān)閉

在線咨詢

Online consultation

  • 在線咨詢
  • 技術(shù)支持

關(guān)注微信公眾號

微信掃一掃立即咨詢

微信掃一掃立即咨詢

關(guān)閉